Mesoestetic Melan Tran3x Concentrate on a warm cream studio background
Mesoestetic Melan Tran3x Concentrate original manufacturer product image

Targeted pigment care

mesoestetic® melan tran3x concentrate

A targeted serum for uneven pigmentation, including melasma and marks left after inflammation.

£108.45 £36.15/10ml
30ml
Best suited to
Uneven pigmentation or post-blemish marks are established concerns and your skin tolerates active serums.
Another option may be better if
The cause of pigmentation is unclear, it is changing, or your skin is reactive or already using several exfoliating products.

Earn 5% back in Curatory Credit

Our way of saying thank you as you build your skincare routine with The Curatory.

How Curatory Credit works

Why I chose it

I chose this for people who want to add a targeted pigmentation step after getting the foundations of their routine right. It may be useful for melasma or marks left after inflammation.

If your pigmentation is new, changing or you’re not sure what it is, arrange an assessment before trying to treat it.

Dr Max GreenfieldMBBS, BSc, MRCS(Eng)

Where this fits

A broad guide to where this sits, without assuming how many steps your routine has.

Comes afterCleansing and any toner or mist
This product mesoestetic® melan tran3x concentrate
Comes beforeOther leave-on products and SPF
Comes afterCleansing and any toner or mist
This product mesoestetic® melan tran3x concentrate
Comes beforeOther leave-on products
Curate your full skincare routine
How to introduce it

Apply 3–4 drops to clean, dry, intact skin once daily. If your skin tolerates it and twice-daily use works with the rest of your routine, you can increase to morning and evening.

During direct sun exposure, use a very high-protection sunscreen and use Melan Tran3x in the evening only.

Guidance continues after purchase. We can help you introduce, simplify or adjust this product.

The ingredients that make this special

A closer look at the ingredients doing the most meaningful work in this formula—and what the evidence can reasonably tell us.

Niacinamide

A form of vitamin B3 that supports the skin barrier and can help with uneven tone and visible redness.

Read the clinical context

Niacinamide is a form of vitamin B3 that supports the skin barrier. Over time, it can help improve the appearance of uneven tone and redness. How much difference it makes depends on the concentration, the rest of the formula and whether the product is left on the skin or is rinsed off.

Tranexamic Acid

An ingredient used to support a more even-looking skin tone.

Read the clinical context

Evidence for topical use in melasma is promising, but it should be viewed as one supportive part of a broader plan rather than a standalone treatment.

Mandelic Acid

An AHA that gently exfoliates and can help improve the look of rough texture and congestion.

Read the clinical context

Mandelic acid is an AHA with a larger molecular size than glycolic acid, so it tends to work more gradually and is often better tolerated. Over time it can help to improve the appearance of rough texture, oily shine and blocked pores.

Salicylic acid

An oil-soluble BHA that exfoliates inside the pore and can help with blackheads and congestion.

Read the clinical context

Salicylic acid is an oil-soluble BHA that helps loosen the mix of dead skin cells and oil that can collect inside pores. Over time it can help to reduce blackheads, congestion and oily shine. How strong it feels will depend on the concentration, the rest of the formulation and whether the product is rinsed off or left on.

Kojic Acid

A brightening ingredient that helps reduce the appearance of dark spots.

Read the clinical context

Kojic Acid is derived from certain fungi and works by inhibiting tyrosinase, the enzyme involved in melanin production. There is moderate clinical evidence supporting its ability to improve hyperpigmentation, particularly when used consistently and in combination with other pigment-regulating ingredients. However, it can be irritating for some skin types, especially at higher concentrations, and stability within formulations can be a challenge. It is most commonly used to help fade uneven pigmentation and support a more even-looking skin tone.

View the complete ingredients list

Aqua, Bis-PEG-12 Dimethicone, Butylene Glycol, Hydroxyethyl Urea, Niacinamide, Tranexamic Acid, Mandelic Acid, Polymethylsilsesquioxane, Lactic Acid, Sodium Citrate, Sodium Hydroxide, Kojic Acid, Plankton Extract, Bacillus Ferment, Acetyl Glycyl Beta-Alanine, Glycogen, Ethylhexylglycerin, Propylene Glycol, Glycerin, Salicylic Acid, Citric Acid, Xanthan Gum, Polyacrylate Crosspolymer-11, Aminoethylphosphinic Acid, Disodium EDTA, Sclerotium Gum, Lecithin, Pullulan, Pentylene Glycol, Sodium Hyaluronate Crosspolymer-2, Silica, Potassium Sorbate, Sodium Metabisulfite, Phenoxyethanol, Parfum.

More about mesoestetic

mesoestetic began in a pharmacy in Barcelona and has developed into a pharmaceutical laboratory working across cosmetic skincare and aesthetic medicine. The company develops and manufactures its products locally, allowing it to oversee formulation, production and quality control.

Research and professional collaboration remain central to its approach. Its range covers concerns including pigmentation, blemish-prone skin, skin ageing and sun protection, with products designed for both everyday skincare and use alongside professional treatment.